Postdoc Fellowships for Female Neuroscientists

In 2011 NeuroCure initiated Postdoc Fellowships for Female Neuroscientists as an intramural funding program to promote early independence for advanced female researchers from the local community who have a strong interest in continuing their career towards an independent faculty position. These two-year fellowships with the option of a one-year extension include funds for personnel, consumables, and small investments, as well as support for childcare and participation in the Charité Mentoring Competence Center.

The impact of this program on career development shines through in our alumnae. 50% of the postdoc fellows from the Cluster’s first two funding periods now lead their own independent research groups, while others continue to make important scientific contributions in other sectors.

We welcome the newest female postdoc fellows in 2021:

Frauke Ackermann

Projekt start date: July 1, 2021

Projekt start date: July 1, 2021 Frauke Ackermann

Affiliation

Deutsches Zentrum für Neuroregenerative Erkrankungen (DZNE)

Research Focus

The research group "Neurological Developmental Disorders" focuses on pontocerebellar hypoplasia, a disease of the brain associated with underdevelopment (hypoplasia) of the cerebellum and bridge. Our research looks at the four areas of the synapse (pre- and postsynapse, glial cells, extracellular matrix), with an emphasis on the role of the extracellular matrix (ECM). We investigate the effects of disorders in the ECM on the development and function of synapses and neuronal circuits and how they influence the onset of neurodevelopmental disorders. We perform our studies in a genetically modified model system as well as in primary cell cultures (neurons, astrocytes). We use cell biological and biochemical methods and combine them with modern light microscopy.

Melissa Herman

Project start date: July 1, 2021

Project start date: July 1, 2021 Melissa Herman

Affiliation

Charité - Universitätsmedizin Berlin

Research Focus

The output of neural circuits depends on the strength and integration of the brain’s building blocks – synapses - releasing excitatory or inhibitory neurotransmitters. A balance of excitation and inhibition within the circuits is crucial for normal brain function. The aim of the project “Functional and molecular diversity of inhibitory and excitatory synapses” is to address whether the molecular mechanisms underlying diversity in function at the synapse level contribute to establishing the excitation/inhibition balance in neural networks. Using electrophysiology, imaging and molecular biology tools, my group will investigate physiological processes at excitatory and inhibitory synapses. By defining how - and why - excitatory and inhibitory synapses behave differently, we will uncover potential pathways to investigate excitation/inhibition imbalanced states, such as in neurological diseases.

Anna Kufner

Project start date: July 1, 2021

Project start date: July 1, 2021 Anna Kufner

Affiliation

Charité - Universitätsmedizin Berlin

Research Focus

The primary aim of Anna Kufner´s research project entitled “Lesion-network mapping (LNM) of post-stroke symptoms” is to identify the role of stroke lesions and their effects on functional brain connectivity in the development of complex post-stroke deficits. The current project will pool MRI and clinical data of >1500 ischemic stroke patients from four large prospective stroke cohorts. As part of a newly established collaboration with the Charité NetStim Lab and Center for Stroke Berlin Neuroradiology, our research group will apply a novel methodology – LNM – to better characterize and subsequently predict a range of post-stroke symptoms including acute delirium, post-stroke depression, long-term cognitive impairment, and cardiac dysfunction. The overarching goal of this collaborative project is to better understand, predict, and ultimately treat these highly clinically relevant post-stroke neurological deficits.

Tania López-Hernández

Project start date: June 1, 2021

Project start date: June 1, 2021 Tania López-Hernández

Affiliation

Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP)

Research Focus

The aim of Tania López-Hernández’s research project “Functional interplay between vesicular trafficking and regulation of ion homeostasis in neurological disorders” is to better understand the role of protein transporters and ion channels in the maintenance of ionic homeostasis for proper brain function, and to elucidate the molecular mechanisms responsible for massive ionic shifts during excitotoxicity, with a special focus on the distinctive responses between neurons and glial cells. I am particularly interested in unraveling the emerging functions of the endosomal Na+/H+ exchangers (NHE) and how alterations in their activity lead to the pathobiology of intellectual disability, autism and other related disorders. Cutting-edge genome engineering in human stem cell-derived neurons and –astrocytes, as well as genetic manipulations with viral vectors will be combined with proteomics, siRNA screenings, live imaging, and sensor-/tracer-based functional assays to study the mechanisms of ion fluxes across intracellular membranes to improve our knowledge about the impact of ions and pH on the regulation of neuronal function and plasticity.

Marta Orlando

Project start date: October 1, 2021

Project start date: October 1, 2021 Marta Orlando

Affiliation

Charité - Universitätsmedizin Berlin

Research Focus

Marta Orlando's research project "Synaptic plasticity in health and disease" focuses on the cellular and molecular mechanisms of learning and memory. She seeks to understand how an imbalance in these processes can lead to neurological disorders. The research focus is on the extent to which the spatial organization of the presynaptic terminal promotes a long-term increase in neurotransmission. The following methods are used in a collaborative and multidisciplinary approach: high-pressure freezing and electron microscopy, live and high-resolution fluorescence microscopy, and electrophysiological and optogenetic stimulation.

Lisa Scheunemann

Project start date: May 1, 2021

Project start date: May 1, 2021 Lisa Scheunemann

Affiliation

Freie Universität Berlin

Research Focus

Lisa Scheunemann's research project "Context-dependent modulation of memory systems" examines the rules according to which the brain stores experiences in long-term memory. The focus is on the inhibitory mechanisms that suppress memory formation and allow it only for certain experiences. I would like to investigate how in particular the physiological context (e.g. diet or stress) influences the evaluation of information and thus could also regulate the selective consolidation of memories. I am particularly interested in the extent to which neuromodulation through serotonin could create an interplay between the physiological state and memory systems. I work with the Drosophila melanogaster model system, as precise genetic tools enable a detailed analysis of molecular and cellular learning mechanisms. Primarily behavioral studies and in vivo imaging are used.

Stephanie Spengler

Project start date: July 1, 2021

Project start date: July 1, 2021 Stephanie Spengler

Affiliation

Charité - Universitätsmedizin Berlin

Research Focus

Previously Awarded Fellowships

2015
Natalia Kononenko

Natalia Kononenko's research project investigated a role of endocytic trafficking in neurotrophin signalling and neurodegeneration. In 2016 Dr. Kononenko moved to the Cluster of Excellence CECAD at the University of Cologne to head a junior research group. Since 2020 she has held a W2 professorship for cellular and molecular physiology at the University Hospital Cologne.

 

Nevena Milenkovic Zujko

Nevena Milenkovic Zujko's research investigated the neural basis of thermal processing and perception in a transgenic mammalian model system, the mouse forepaw.

Ulrike Pannasch

Ulrike Pannasch's research focused on the interplay between astrocytes and neurons during synaptic transmission and plasticity. In November 2015 Dr. Pannasch was recruited as Scientific Coordinator by the College for Life Sciences Berlin. She currently works as a program officer at the Einstein Foundation Berlin.

Miranka Wirth

Miranka Wirth's research project investigated neurophysiological mechanisms and determinants of brain and cognitive health. In 2019 Dr. Wirth moved to Dresden to lead a research group on brain resilience at the DZNE.

2014
Anna Carbone

Anna Carbone's research project examined the biophysical mechanisms governing the activity and interaction of AMPAR-TARP complexes, and the role of AMPARs and TARPs in synaptic plasticity and disease. In 2017 Dr. Carbone moved to Hamburg to work as a research scientist at Evotec.

Tamar Dugladze

Tamar Dugladze's research project focused on the mechanisms of signal flow in the nervous system, and the relevance of these mechanisms in the genesis of seizures and epilepsy.

2011
Tatiana Korotkova

Tatiana Korotkova's research project focused on the interactions between subgroups of hypothalamic neurons as well as the regulation of hypothalamic circuits by cortical afferents. In 2017 Dr. Korotkova moved to Cologne to head a research group at the MPI Institute for Biology of Ageing. She is currently a full (W3) professor and managing director of the Institute for Vegetative Physiology at the Faculty of Medicine, University of Cologne.

Veronica Witte

Veronica Witte's research project investigated whether caloric restriction or other dietary modifications can improve cognitive functions and surrogate markers of beginning cognitive decline in healthy elderly subjects, and in patients with mild cognitive impairment (MCI). In 2014 Dr. Witte moved to Leipzig to head a research group at the MPI for Human Cognitive and Brain Sciences.